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Correlation between number of blastocysts generated and probability of having a baby

There is a direct correlation between the capacity to produce one or more blastocysts and the higher probability of having a livebirth. However, this relationship has a limit.

The capacity to generate blastocysts (5th to 6th day embryos) depends on multiple factors associated with the woman’s health and, above all, her age. This also strongly depends on the quality of the lab where the embryo culture is performed. If a woman produces more than one blastocyst, several possibilities are open; the most important of which is being able to freeze one or more and transfer them in the future. In this way, her chance of being a mother will be the sum of the fresh transfer plus the transfer of frozen embryos. This is called cumulative probability, referred to in chapter 7. However, besides increasing the cumulative probability, the chance of having a child by fresh blastocyst transfer increases if the woman has been able to freeze one, two or three additional blastocysts.

As seen in Figures 16, 17 and 18, the probability of birth after the transfer of a fresh embryo is significantly higher if the woman can freeze at least one additional blastocyst, and this probability keeps rising with two and even three additional frozen blastocysts. This is understandable, because if a woman or couple can produce several blastocysts, they had generated several eggs, and they are more reproductively efficient than women or couples who can produce only one.

Figure 16. Delivery rate by fresh transfer after transferring one blastocyst according to woman’s age and number of vitrified blastocysts from the same cohort.

Figure 17. Delivery rate by fresh transfer after transferring one blastocyst according to woman’s age and number of vitrified blastocysts from the same cohort.

Figure 18. Delivery rate by fresh transfer after transferring one blastocyst according to woman’s age and number of vitrified blastocysts from the same cohort.